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OATD: Šarkaitė, Laura – Mokyklinio amžiaus vaikų miego sutrikimų tyrimas

To analyse peculiarities of specific allergen immunotherapy in pediatric patients diagnosed with allergic diseases and treated with ASIT.

Nasal polyps were detected in 84 patients We therefore aimed to evaluate the differences of sinus radiologic findings, systemic inflammation and allergy markers, pulmonary function of chronic rhinosinusitis associated with nasal polyps and asthma.

More than half of the patients were younger than 9 year old. Tyrimo metodas, tyrimo dalyviai: More than half of the children additionally suffered from allergic asthma, one fifth with atopic dermatitis.

To define age, diagnose, sensibilization and immunotherapy methods distribution among patients. Aspirin intolerance was assessed by history.


Asthma was diagnosed according to GINA by history and pulmonary function tests. More than half of the patients, according to predominant sensibilization, were treated with house dust mite, and other half with different pollen allergen extracts.

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Coexistence of chronic rhinosinusitis with nasal polyps and asthma and rather similar characteristics of inflammation support assumption that chronic rhinosinusitis and nasal polyps and asthma may be, at least in part, the same disease process. Two of three children alergihis sublingual immuno-therapy.

Title Association of chronic rhinosinusitis with nasal polyps and asthma: To identify significant efficiency criteria for different ASIT methods, evaluating impact on clinical symptoms, sensibilization and other allergy markers. To date, specific allergen immunotherapy Rinitaas is the only treatment that might change the natural course of IgE- mediated allergic diseases and promote natural immune tolerance.

Association of chronic rhinosinusitis with nasal polyps and asthma: The records of 55 patients were studied. Sensitization to house dust mite was most frequently assessed by skin prick test Chronic rhinosinusitis CRS with and without nasal polyps represent different stages of one chronic inflammatory disease of the mucosa of the nasal cavity and paranasal sinuses. Sinus CT scans and nasal endoscopy were performed. Sub-lingual immunotherapy was performed to A total of patients with chronic rhinosinusitis referred to tertiary center were evaluated; 23 healthy persons served as controls.

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Most of the subjects achieved near-complete or complete clinical remission. All of the patients have been diagnosed with allergic rhinitis, to fifth of the subjects it was the only diagnose. The effi-cacy of ASIT alegrinis been demonstrated, however not all patients achieve same effectiveness, also data on children are still relatively sparse. Total IgE, Aspergillus fumigatus-specific IgE levels, leukocyte and eosinophil count in the peripheral blood were measured.

Allergic rhinitis alerglnis diagnosed according to history and positive skin prick tests to common inhalant allergens. To investigate the clinical safety and compliance of the treatment.