LEI 11418 PDF

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Leu weight and BMD were both significantly decreased in osteoporotic rats, although BMD was partially restored by intraperitoneal morin administration. Find all citations in this journal default. In the latter case, please turn on Javascript support in your web browser and reload this page.

Gene Ontology GO Terms. Morin treatment also increased the number of lek bones in DEX-induced rats. It is said that GBE treatment could avoid drug-induced obesity.

Read Article at publisher’s site. Either your 14118 browser doesn’t support Javascript or it is currently turned off. We investigated the effects of GBE on glucose consumption, glucokinase activity, and mRNA levels of key genes in glucose metabolism and the insulin signaling pathway.

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Europe PMC requires Javascript to function effectively. Pathological examination was performed by hematoxylin and eosin staining.

How does Europe PMC derive its citations leu No matching affiliation detected. Furthermore, after analyzing gene expression, we suggest that GBE chiefly exerts its effects by stimulating IRS-2 transcription. Journal of Natural Medicines [03 Sep65 1: Europe PMC requires Javascript to function effectively.

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How does Europe PMC derive its citations network? Our data suggest that GBE has the potential to prevent insulin resistance and is a promising anti-diabetic drug. Journal of Natural Medicines [24 Jul72 4: CitePeer Related Articles http: In the latter case, please turn on Javascript support in your web browser and reload this page.

To better show its efficacy, we included a control group that was treated with rosiglitazone, a type of thiazolidinedione TZD.

It should be noted that, unlike rosiglitazone, GBE did not stimulate excessive glucose uptake as it improved glucose tolerance. Either your web browser doesn’t support Javascript or it is currently turned off.

Abstract Ginkgo biloba, an herbal medication, is capable of lowering glucose, fat, and lipid peroxide in diabetic patients.

Or filter your current search. Or filter your current search. The relative expression of osteogenic and lsi resorption markers was determined by real-time polymerase chain reaction and Western blotting, respectively. Body weight was regularly monitored.

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The data ,ei that GBE repressed glucose uptake under normal conditions, while it dramatically improved glucose tolerance under insulin-resistant conditions. Abstract Our aim is to investigate the potential therapeutic value of morin against osteoporosis and elucidate the mechanism of action.

Read Article at publisher’s site.

Mechanistically, morin reversed the decrease of osteogenic markers and increase of bone resorption markers, which might eventually be mediated by modulation of MAPK signaling cascades. Gene Ontology GO Terms. Body mineral density BMD was determined at proximal femurs using dual energy X-ray absorptiometry.

Here, we uncovered the therapeutic effect of morin against osteoporosis and demonstrated its suppressive action on the MAPK pathway in this disease. In the current study, we tested the hypothesis that Ginkgo biloba extract GBE prevented hyperinsulinism-induced glucose intolerance in hepatocytes.

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