Caesalpinia sappan L. (Leguminosae) is found in India, Malaysia, southern China, and tropical Asia, and its heartwood Sappan lignum is used as a red dye. Family Name: Fabaceae (Leguminosae). Common Names: Sappan Wood, Brazilwood Tree, Sappan. Chinese Name: 苏木. by; G. Renu, Sanjana Julias Thilakar, D. Narasimhan, Centre for Floristic Research, Department of Botany, Madras Christian College, Tambaram. (0 ratings).

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Caesalpinia sappan L. | Species | India Biodiversity Portal

Paw swelling was most severe upto 3. The wood of Caesalpinia sappan is the wood-dye that is known to have been used at a large, international scale throughout world history. All extracts stimulated osteoblast proliferation and exhibited anti-osteoporosis activities [ 31 ]. It also is a good source of firewood.

Biancaea sappan Leaves and fruits Conservation status.

Caesalpinia sappan L.

Click on “show more” to view them. Background Rheumatoid arthritis RA is a systemic inflammatory disease of the synovium, cartilage, and bone. Brazilin formed a single homogenous peak under preparative HPLC conditions, with a retention time of 7.

Although RA is not inherited, certain human RA susceptible genes may be triggered in response to infection or environmental factors, establishing an autoimmune condition wherein the immune system begins to produce substances that attack the joints. Bharat Bhusan Patnaik, Email: The detection voltage and interface temperature were 1. Brazilin exhibits various biological activities including anti-hyperglycemic [ 15 ], anti-hepatotoxic [ 14 ], and anti-inflammatory effects [ 17 ].


Sappanwood would then provide a renewable source of colorant, not only in the textile and basket-weaving crafts but also in the food, cosmetic and pharmaceutical industries. Retrieved from ” https: Then the paper can be hammered. Several recent studies have focused on herbal extracts or compounds that exhibit anti-arthritic effects in rats with adjuvant-induced arthritis [ 11 – 13 ].

The chemical structure of brazilin is shown below. PLoS Biol No serious diseases and pests have been reported, although fungi such as Auricularia auricula-judae the edible Judas ear mushroom and Meliola caesalpiniae can attack the trees. Please review our privacy policy. It does not tolerate too wet soil conditions. It is reduced to small fragments which are soaked for several hours in a heated bath.

Harvesting is done manually with a machete; prickles are easily removed by brushing with the blunt edge of the machete. Encyclopedia of Life EOL. The serum levels of inflammatory mediators decreased after administration of brazilin in the present study that is in agreement to the several reports on attenuation of rat CIA by heartwood extracts of C. The BMD decreases in control group may be attributable to increased bone surface erosion and decreased trabecular thickness.

Thiruvananthapuram District harbours more than 1, medicinal plants of which plants are hosts Citation in news articles. Email this to a friend Print Share on facebook Tweet this.

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The main dye component in the heartwood of Caesalpinia sappan is brazilin, also present in brazilwood Caesalpinia echinata Lam. N – trabecular number; Tb.


Brazilin modulates immune function mainly by augmenting T cell activity in halothane administered mice. Sappanwood salpan a major trade good during the 17th century, when it was sqppan from Southeast Asian nations especially Siam aboard red seal ships to Japan.

Caesalpinia sappanRheumatoid arthritis, Collagen-induced arthritis, Brazilin, Pro-inflammatory cytokines.

CambodiaChina Cultivated. Significant reductions in the cytokine levels were evident upon treatment with either MTX or brazilin, compared to the control group. Abatacept therapy for rheumatoid arthritis in the setting of hepatitis C infection. Caesalpinia sappan Sappan Wood Caesalpinia sappan; Brazilin isolated from C.

Microstructural bone examination using microfocal computed tomography micro-CT The microstructures of the distal end of the left femur, the proximal end of the left tibia, the distal end of the left calcaneus, and the distal end of the left second metatarsal bone, were analyzed via high resolution micro-CT SkyScanBruker, Antwerp, Belgium. There are 2 citations in Afrirefs related to Caesalpinia sappan L. There are 20 study abstracts related to Caesalpinia sappan L. The left tibial metaphysis and the distal part of the left femur of the control group were thin and distorted, compared with those of the normal group.

Steroidal lactones from Withenia somneferaan ancient plant for novel medicine.