Merkel-cell carcinoma (MCC) is a rare and highly aggressive skin cancer, which, in most cases, is caused by the Merkel cell polyomavirus (MCPyV or MCV). Merkel cell carcinoma, also called neuroendocrine carcinoma of the skin or trabecular cancer, is a very rare type of skin cancer that forms when. Los hallazgos clínicos más característicos son el rápido crecimiento y la ausencia de dolor. Aunque el carcinoma de células de Merkel puede afectar cualquier.

Author: Maubei Dorn
Country: Ecuador
Language: English (Spanish)
Genre: Finance
Published (Last): 18 August 2013
Pages: 472
PDF File Size: 14.65 Mb
ePub File Size: 3.39 Mb
ISBN: 824-7-11782-239-6
Downloads: 61925
Price: Free* [*Free Regsitration Required]
Uploader: Fesho

The purpose of Wikipedia is to present facts, not to train. MCC is not a very common skin cancer.

Annals of Surgical Oncology. D ICD – Journal of Oral and Maxillofacial Pathology. Complete excision is associated with significant higher survival rates. In addition, the virus has a particular mutation only when found in cancer cells, but not when it is detected in healthy skin cells. Regular self-examination of the skin should be done every month and a check once a year with a qualified dermatologist.

This page was last edited on 28 Octoberat Cells se nearly any part of the body can become cancer, and can then celula to other parts of the body. Cover exposed skin with broad-brimmed hat and clothing. Sinceit has been known that other primary cancers increase the mer,el of MCC significantly, especially in those with the prior multiple myeloma, chronic lymphocytic leukemiaand malignant melanoma.

The other dangerous skin cancer is melanoma.

Merkel-cell carcinoma – Wikipedia

As ofMCC occurred 30 times more often in people with chronic lymphocytic leukemia and Immunofluorescence studies and electronic microscopy allowed the cell of origin of this pathology to be identified in Merkel-cell carcinoma is a rare skin cancer of neuroendocrine origin, which has been described as the most aggressive skin malignancy. The authors believe that the proper approach to this type of cases should include a study by the sentinel lymph node technique to detect micrometastases.


Dd existence of satellite lesions and cutaneous spread should be investigated and lymphatic drainage chains should be palpated. It varies depending on the stages of the cancer.

[Merkel cell carcinoma experience in a reference medical center.]

The most frequent locations include: From Wikipedia, the free encyclopedia. Ann Surg Oncol Carcinooma Primary cutaneous neuroendocrine Merkel cell or trabecular carcinoma tumour of the skin: It has been shown to be effective in reducing the rates of recurrence and in increasing the survival of patients with MCC.

Trabecular carcinoma of the skin.

Radiotherapy at a dose of 60 Gy also has been used alone, obtaining adequate levels of local control, which supports the characterization of this tumor as radiosensitive. July Learn how and when to remove this template message. To learn more see What Is Cancer?

Cervical CT did not disclose cervical lymph node involvement. Aggressive digital papillary adenocarcinoma Extramammary Paget’s disease.

This section with questionable factual accuracy needs more medical references for verification or relies too heavily on primary sources.

Carcinoma cutáneo de células de Merkel: Presentación de un caso y revisión de la literatura

They usually don’t hurt, but they’re fast-growing and can sometimes open up as ulcers or sores see Signs and Symptoms of Merkel Cell Carcinoma. There was a significant benefit of adjuvant nodal therapy, but only when the SLNB was positive.

Although MCC’s may arise almost anywhere on the body, about half originate on sun-exposed areas of merkell head and neck, one-third on the legs, and about one-sixth on the arms.


Inthe annual incidence rate was around 0. No cervical lymph nodes were palpated. A clinical case of Merkel cell carcinoma of the face carcinomx with surgery and radiotherapy is reported and the literature is reviewed.

Palacios 1J. For that reason, some authors recommend initial surgical treatment of cervical lymph nodes due to the risk of cervical metastasis and the poor prognosis. With epidermal involvement Eczematous contact dermatitis atopic dermatitis seborrheic dermatitis stasis dermatitis lichen simplex chronicus Darier’s disease glucagonoma syndrome langerhans cell histiocytosis lichen sclerosus pemphigus foliaceus Wiskott—Aldrich syndrome Zinc deficiency.

What Is Merkel Cell Carcinoma?

MCV is a common human infection carcimoma can be detected by conformational capsid epitope immunoassays”. American Journal of Clinical Pathology. Infectious diseases — viral systemic diseases A80—B34— Ann Surg Oncol ;8: Current Opinion in Oncology.

The incidence of MCC is increased in conditions with defective immune functions such as malignancy, HIV infection, and organ transplant patients, etc. Case description A 72 year-old woman was seen in our clinic for a rapidly growing, nodular, erythematous skin lesion with a shiny surface Figs. The Journal of Pathology. European consensus-based interdisciplinary guideline”. The Journal of Clinical Investigation.

Because Merkel cells are a type of neuroendocrine cell, Merkel cell carcinoma MCC is also sometimes called neuroendocrine carcinoma of the skin. The tumor arises from the Merkel cells, or skin pressure receptors.