When isolated from clinical specimens, nondiphtherial Corynebacteria, such as Corynebacterium striatum, Corynebacterium amycolatum. ABSTRACT. We describe an unusual cluster of Corynebacterium striatum infections in 21 patients with chronic obstructive pulmonary disease (COPD) admitted. Objective: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. Methods: A.

Author: Yozshumuro Gukinos
Country: Brazil
Language: English (Spanish)
Genre: Travel
Published (Last): 20 March 2011
Pages: 224
PDF File Size: 9.95 Mb
ePub File Size: 8.67 Mb
ISBN: 690-4-88056-873-4
Downloads: 56485
Price: Free* [*Free Regsitration Required]
Uploader: Tobei

Van Hoek AH, et al. Patients suffering underlying diseases and receiving multiple antibiotic courses are at high risk for developing serious opportunistic infections by drug-resistant C. Verroken A, et al.

Corynebacterium striatum: a diphtheroid with pathogenic potential.

No bacteria species could be identified at this time. Ethics statement This study was performed in accordance with the ethical guidelines of the Declaration of Helsinki The presence of aminoglycoside modifying enzyme AME genes common in Corynebacterium spp.

Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: Successful treatments of C.

Although patients with implanted CRT-D may develop infectious endocarditis, obvious vegetation was never observed on corynebacerium in these cases [ 11 ]. The nonlipophilic bacteria may be classified as fermentative and nonfermentative:. Therefore, two sets of blood samples for blood culture were collected. Shriatum production is specific to C. They are widely distributed in nature in the microbiota of animals including the human microbiota and are mostly innocuous, most commonly existing in commensal relationships with their hosts.

Tobramycin was also very active 56 isolates were susceptible. Corynebacterium diphtheriae Diphtheria Corynebacterium minutissimum Erythrasma Corynebacterium jeikeium Group JK corynebacterium sepsis. In Ford, Marvella E.


These enzymes are up-regulated in industry through genetic engineering to ensure adequate amounts of lysine precursors are produced to increase metabolic flux. Susceptibility to aminoglycosides and distribution of aph and aac 3 -XI genes among Corynebacterium striatum clinical isolates. A spontaneous joint infection with Corynebacterium striatum.

Many genetic manipulations conducted in industry are by traditional cross-over methods or inhibition of transcriptional activators.

Upon antibiotic administration, a selective pressure is created in body organs where fluoroquinolones tend to accumulate. Therefore, in this case, appropriate antibiotics could not be judged in vivo.

In conclusion, this study highlights the relevance of C. A year-old woman was brought to our emergency department because of exertional dyspnea due to severe left ventricular functional failure.

Corynebacterium striatum Bacteremia Associated with a Catheter-Related Blood Stream Infection

Isolates were classified as resistant, intermediate, or susceptible, according to criteria defined by CLSI This cluster is distinguished by several conserved signature indels, such as a two-amino-acid insertion in LepA corynebacteriim a seven- or eight-amino-acid insertions in RpoC. The mef A-E gene was not found in any strain tested.

Expression of functionally active human epidermal growth factor has been brought about in C. As with various species of a microbiota including their cousins in the genera Arcanobacterium and Trueperellathey usually are not pathogenic but can occasionally opportunistically capitalize on atypical access to tissues via corynebacteriuk or weakened host defenses. In terms of nutritional requirements, all need biotin to grow. Sixty-three out of the 90 strains were identified as putative C.


Corynebacterium striatum: a diphtheroid with pathogenic potential.

Clinical and Laboratory Standards Institute Corynebacterium striatum pneumonia in an HIV patient. Gram-positive bacilli were detected in both blood culture samples; each set included aerobic and anaerobic cultures Figures 1 b and 1 c.

This work highlights the high prevalence of multi-resistant strains and resistance genes striztum the C. Enzymatic inactivation of the antibiotic molecule is the most prevalent in the clinical setting. Unwanted side reactions such as threonine and asparagine production can occur if a buildup of intermediates occurs, so scientists have developed mutant strains of C.

All strains were susceptible to vancomycin, linezolid, and daptomycin. Retrieved from ” https: Our results indicate that amikacin is the preferable aminoglycoside for striztum of C. Mutations corjnebacterium gyrA were identified by aligning sequences of resistant isolates to the sequence of C. Methods Bacterial strains and growth conditions During the period —, 90 strains recovered from clinical specimens submitted for routine culture to the microbiology laboratory of the FHU hospital were assigned to ckrynebacterium genus Corynebacterium on the basis of colony morphology, Gram staining, and catalase production.

Although the biochemical properties of C.

A variety of Gram-positive bacteria carry mobile mef genes.