Hyper-CVAD regimen for NHL and ALL: Part A: Cyclophosphamide, Vincristine, Doxorubicin, Dexamethasone. Contact Physician. HYPERCVAD Regimen. Cyclophosphamide-Vincristine-Doxorubicin- Dexamethasone-Methotrexate-Leucovorin-. Cytarabine. Disease Site. Modification of the hyper-CVAD regimen with anthracycline intensification did not improve outcome. Other modifications of the program could include.

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Drink plenty of fluids — at least two litres three and a half pints during the 24 hours after chemotherapy.

Constipation This treatment can cause constipation. Other medicines Some medicines can affect chemotherapy or be harmful when you are having it. Symptoms of raised blood sugar include: Day 3 — you have two protcool drips of cytarabine.

Cyclophosphamide Vincristine Doxorubicin also called Adriamycin Dexamethasone a steroid. Your doctor or nurse may prescribe creams to improve the symptoms. The side effects of the administration of the chemotherapeutic agents used in hyper-CVAD are complex, and are often dependent on the overall health of the patient. You will have blood tests to check how well your liver is working. You will be given hyper-CVAD during a stay in hospital or in the chemotherapy day unit.

Steroids can make you feel much hungrier than usual and you may gain weight. Once the treatment has ended, any changes usually take a few months to grow out. Discoloured urine Doxorubicin may make your urine a pink-red colour for up to 48 hours after you have had the treatment. It encourages the body to make more white blood cells. We cannot list every side effect for this treatment.

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So far as is permitted by law, Macmillan does not accept liability in relation to the use of any information contained in this publication progocol third party information or websites cvav or referred to in it. You may feel drowsy, confused, dizzy or unsteady.

Hyper-CVAD chemotherapy – Macmillan Cancer Support

If you have pain or notice any change in your vision, always tell your doctor or nurse. If the number of white blood hyperr is low, you are more likely to get an infection. Your nurse can talk to you about ways to cope with hair loss. This is the last week in the cycle of hyper-CVAD. Dexamethasone is given as tablets or an injection into your line. The kidneys usually get rid of uric acid, but may not be able to cope with large amounts.

Your doctor may give you G-CSF: You can also watch tutorials on wigs, headwear and eye make up. If you have an infection, it is important to treat it as soon as possible. Retrieved from ” https: The doctor numbs an area of skin over your spine with local anaesthetic.

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Feeling sick You may feel sick in the first few days after chemotherapy. Medical and dental treatment If you need medical treatment for any reason other than cancer, always tell the doctors and nurses that you are having cancer treatment.

A variety of antiemetic drugs may be used, including granisetronondansetronmetoclopramide and cyclizine.


Ccad your doctor or nurse if you have these symptoms. Your nurse will give you advice about managing your side effects. Blood clot risk Cancer and some cancer treatments can increase the risk of a blood clot. You take them for four days days 1 to 4. Your nurse will give you telephone numbers for the hospital. Steroids may cause your ankles and legs to swell because of fluid building up.

The leaflet lists all known side effects. This treatment may cause severe diarrhoea. But if you have hyper-CVAD before a stem cell transplant, you usually only have two cycles of each schedule.

A company limited by guarantee, registered in England and Wales company number The majority of patients will experience a degree of pancytopeniaincluding anaemiathrombocytopeniaand leukopeniadue to the myelosuppressive effect of chemotherapy. Temporary hair loss is a common side effect. Hyper-CVAD can cause side effects. If you’re struggling to find what you need, call our Support line on Monday to Friday, 9am-8pm.

Rarely, hyper-CVAD can affect the nervous system. You also have two drips of cytarabine. Tummy pain or indigestion Steroids can irritate the stomach lining. Your course of hyper-CVAD. You will have a blood test before having more chemotherapy.

The chemotherapy drugs can be given through: Your doctor or nurse can tell you what to expect.